≡

SAP Domain Containing Ribonucleoprotein (SARNP)

[Edit]

CIP29; HCC1; THO1; Cytokine Induced Protein 29 kDa; Hepatocellular Carcinoma 1; Nuclear protein Hcc-1; Proliferation-associated cytokine-inducible protein CIP29

SAP Domain Containing Ribonucleoprotein (SARNP)
CCC J372
HGNC 24432
MGI 1913368
UniProt P82979
Wiki CIP29
SARNP contains an N-terminal SAP DNA-binding motif, 2 nuclear localization signals, 3 potential N-glycosylation sites, and 9 potential phosphorylation sites. Northern blot analysis detected CIP29 expression in most adult tissues examined. Expression was higher in fetal brain, kidney, liver, heart, and thymus compared with adult tissues.
CIP29 expression was elevated in all solid tumors examined and was higher in myeloid leukemia and lymphoma cell lines than in normal adult bone marrow and lymph node.CIP29 expression was upregulated by erythropoietin (EPO) in erythroleukemic UT7/Epo cells and by thrombopoietin (THPO), FLT3 ligand (FLT3LG), and stem cell factor (KITLG) in primary human CD34-positive cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SAP Domain Containing Ribonucleoprotein (SARNP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SAP Domain Containing Ribonucleoprotein (SARNP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SAP Domain Containing Ribonucleoprotein (SARNP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SAP Domain Containing Ribonucleoprotein (SARNP) CLIA Kit Customized Service Offer
n/a ELISA Kit for SAP Domain Containing Ribonucleoprotein (SARNP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SAP Domain Containing Ribonucleoprotein (SARNP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SAP Domain Containing Ribonucleoprotein (SARNP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SAP Domain Containing Ribonucleoprotein (SARNP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SAP Domain Containing Ribonucleoprotein (SARNP) CLIA Kit Customized Service Offer
n/a ELISA Kit for SAP Domain Containing Ribonucleoprotein (SARNP) ELISA Kit Customized Service Offer
  1. "An integrated approach in the discovery and characterization of a novel nuclear protein over-expressed in liver and pancreatic tumors."FEBS Lett. 496:109-116(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and characterization of a proliferation-associated cytokine-inducible protein, CIP29."Biochem. Biophys. Res. Commun. 292:593-600(2002) [PubMed] [Europe PMC] [Abstract]
  3. "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells." Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. , Submitted (JUL-2004) to UniProtKB
  7. "Hcc-1 is a novel component of the nuclear matrix with growth inhibitory function."Cell. Mol. Life Sci. 61:2264-2273(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Intracellular characterization of DDX39, a novel growth-associated RNA helicase."Exp. Cell Res. 313:782-790(2007) [PubMed] [Europe PMC] [Abstract]
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  10. "ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex."Genes Dev. 24:2043-2053(2010) [PubMed] [Europe PMC] [Abstract]
  11. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  12. "Solution structure of the SAP domain of human nuclear protein HCC-1."Submitted (OCT-2006) to the PDB data bank