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Chromatin Modifying Protein 2A (CHMP2A)

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BC2; CHMP2; VPS2; Charged Multivesicular Body Protein 2a; Putative Breast Adenocarcinoma Marker; Vacuolar protein sorting-associated protein 2-1

Chromatin Modifying Protein 2A (CHMP2A)
CCC J383
HGNC 30216
MGI 1916203
PubMed 15173323
RGD 1305050
UniProt O43633
Wiki CHMP2A
CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III , a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.
The deduced 222-amino acid mouse protein contains N- and C-terminal coiled-coil regions. Northern blot analysis detected Chmp2a expression in most mouse tissues examined, with highest levels in heart, brain, liver, and kidney. Immunofluorescence microscopy localized Chmp1a mainly to the cytoplasm.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromatin Modifying Protein 2A (CHMP2A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromatin Modifying Protein 2A (CHMP2A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromatin Modifying Protein 2A (CHMP2A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromatin Modifying Protein 2A (CHMP2A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromatin Modifying Protein 2A (CHMP2A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromatin Modifying Protein 2A (CHMP2A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromatin Modifying Protein 2A (CHMP2A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromatin Modifying Protein 2A (CHMP2A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromatin Modifying Protein 2A (CHMP2A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromatin Modifying Protein 2A (CHMP2A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromatin Modifying Protein 2A (CHMP2A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromatin Modifying Protein 2A (CHMP2A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromatin Modifying Protein 2A (CHMP2A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromatin Modifying Protein 2A (CHMP2A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromatin Modifying Protein 2A (CHMP2A) ELISA Kit Customized Service Offer
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  9. ErratumProc. Natl. Acad. Sci. U.S.A. 100:152845-152845(2003)
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  11. "Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis."EMBO J. 26:4215-4227(2007) [PubMed] [Europe PMC] [Abstract]
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  13. "Novel interactions of ESCRT-III with LIP5 and VPS4 and their implications for ESCRT-III disassembly."Mol. Biol. Cell 19:2661-2672(2008) [PubMed] [Europe PMC] [Abstract]
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  15. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  16. "Mechanism of inhibition of retrovirus release from cells by interferon-induced gene ISG15."J. Virol. 85:7153-7161(2011) [PubMed] [Europe PMC] [Abstract]
  17. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]