≡

Chromatin Accessibility Complex 1 (CHRAC1)

[Edit]

CHRAC15; YCL1; Histone-Fold Protein CHRAC15; Chromatin accessibility complex 15 kDa protein; DNA polymerase epsilon subunit p15

Chromatin Accessibility Complex 1 (CHRAC1)
CCC J390
HGNC 13544
MGI 2135796
PubMed 24148822
RGD 1309321
UniProt Q9NRG0
CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
The deduced 129-amino acid protein is highly acidic and contains a short N terminus, a central 65-amino acid histone-fold motif, and a short C terminus that is rich in lysine and acidic residues. The authors noted that there is a high degree of phylogenetic conservation that extends beyond the histone-fold motif. Northern blot analysis revealed expression of a 1.2-kb transcript in all mouse cell lines tested.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromatin Accessibility Complex 1 (CHRAC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromatin Accessibility Complex 1 (CHRAC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromatin Accessibility Complex 1 (CHRAC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromatin Accessibility Complex 1 (CHRAC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromatin Accessibility Complex 1 (CHRAC1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromatin Accessibility Complex 1 (CHRAC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromatin Accessibility Complex 1 (CHRAC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromatin Accessibility Complex 1 (CHRAC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromatin Accessibility Complex 1 (CHRAC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromatin Accessibility Complex 1 (CHRAC1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromatin Accessibility Complex 1 (CHRAC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromatin Accessibility Complex 1 (CHRAC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromatin Accessibility Complex 1 (CHRAC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromatin Accessibility Complex 1 (CHRAC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromatin Accessibility Complex 1 (CHRAC1) ELISA Kit Customized Service Offer
  1. "HuCHRAC, a human ISWI chromatin remodelling complex contains hACF1 and two novel histone-fold proteins."EMBO J. 19:3377-3387(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  11. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]