≡

Carbohydrate Sulfotransferase 5 (CHST5)

[Edit]

Gn6st-3; GST4-alpha; Intestinal N-acetylglucosamine-6-O-sulfotransferase; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-alpha

Carbohydrate Sulfotransferase 5 (CHST5)
CCC J395
HGNC 1973
MGI 1931825
PubMed 10491328
RGD 1561144
UniProt Q9GZS9
Wiki CHST5
The carbohydrates of glycoconjugates are highly diverse structures with variation in monosaccharide composition, glycosidic linkage positions, and branching of chains. Further diversity is added by the covalent addition of sulfate moieties to particular hydroxyl groups and amino groups of saccharides. They can have a profound effect on the physiochemical properties of the glycoconjugates, at least in part through the addition of negative charge.
CHST5 belongs to the GST family of sulfotransferases, which also includes CHST1, CHST2, CHST3, and LSST. These enzymes are 6-O-sulfotransferases, which add sulfate to C6 of galactose (Gal), N-acetylgalactosamine (GalNAc), or N-acetylglucosamine (GlcNAc).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Carbohydrate Sulfotransferase 5 (CHST5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Carbohydrate Sulfotransferase 5 (CHST5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Carbohydrate Sulfotransferase 5 (CHST5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Carbohydrate Sulfotransferase 5 (CHST5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Carbohydrate Sulfotransferase 5 (CHST5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Carbohydrate Sulfotransferase 5 (CHST5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Carbohydrate Sulfotransferase 5 (CHST5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Carbohydrate Sulfotransferase 5 (CHST5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Carbohydrate Sulfotransferase 5 (CHST5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Carbohydrate Sulfotransferase 5 (CHST5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Carbohydrate Sulfotransferase 5 (CHST5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Carbohydrate Sulfotransferase 5 (CHST5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Carbohydrate Sulfotransferase 5 (CHST5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Carbohydrate Sulfotransferase 5 (CHST5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Carbohydrate Sulfotransferase 5 (CHST5) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of a mammalian N-acetylglucosamine-6-sulfotransferase that is highly restricted to intestinal tissue."Biochem. Biophys. Res. Commun. 263:543-549(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene."Nat. Genet. 26:237-241(2000) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Sulfation of endothelial mucin by corneal keratan N-acetylglucosamine 6-O-sulfotransferase (GST-4beta)."Biochem. Biophys. Res. Commun. 282:928-933(2001) [PubMed] [Europe PMC] [Abstract]
  5. "Ectopic expression of a GlcNAc 6-O-sulfotransferase, GlcNAc6ST-2, in colonic mucinous adenocarcinoma."Glycobiology 12:379-388(2002) [PubMed] [Europe PMC] [Abstract]
  6. "Enzymatic synthesis in vitro of the disulfated disaccharide unit of corneal keratan sulfate."J. Biol. Chem. 277:42505-42513(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Activities and expression pattern of the carbohydrate sulfotransferase GlcNAc6ST-3 (I-GlcNAc6ST): functional implications."Glycobiology 13:245-254(2003) [PubMed] [Europe PMC] [Abstract]
  8. "Golgi localization of carbohydrate sulfotransferases is a determinant of L-selectin ligand biosynthesis."J. Biol. Chem. 278:40282-40295(2003) [PubMed] [Europe PMC] [Abstract]