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Component Of Oligomeric Golgi Complex 1 (COG1)

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LDLB; Low Density Lipoprotein Receptor Defect B Complementing; Conserved oligomeric Golgi complex subunit 1

Component Of Oligomeric Golgi Complex 1 (COG1)
CCC J411
HGNC 6545
MGI 1333873
PubMed 17220172
RGD 1304594
UniProt Q8WTW3
Wiki COG1
COG1 is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.
The deduced 980-amino acid cytoplasmic human protein is 82% identical to the mouse sequence. Expression of the mouse gene in ldlB Chinese hamster ovary (CHO) cells corrected their LDLR deficiency, which includes N- and O-glycosylation defects. RT-PCR analysis detected ubiquitous expression that was highest in liver, testis, and ovary. Within brain, expression was highest in amygdala, subthalamic nucleus, thalamus, and cerebellum.

Organism species: Homo sapiens (Human)

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Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Component Of Oligomeric Golgi Complex 1 (COG1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Component Of Oligomeric Golgi Complex 1 (COG1) Monoclonal Antibody Customized Service Offer
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Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Component Of Oligomeric Golgi Complex 1 (COG1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Component Of Oligomeric Golgi Complex 1 (COG1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Component Of Oligomeric Golgi Complex 1 (COG1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Component Of Oligomeric Golgi Complex 1 (COG1) CLIA Kit Customized Service Offer
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