≡

Component Of Oligomeric Golgi Complex 4 (COG4)

[Edit]

COD1; Conserved oligomeric Golgi complex subunit 4

Component Of Oligomeric Golgi Complex 4 (COG4)
CCC J414
HGNC 18620
MGI 2142808
PubMed 19651599
RGD 1310549
UniProt Q9H9E3
Wiki COG4
Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG4. The deduced 785-amino acid COG4 protein contains an N-terminal coiled-coil region. Coiled-coil regions are found in all members of the COG complex and may be involved in holding the complex together or in binding other proteins involved in vesicle docking and fusion.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Component Of Oligomeric Golgi Complex 4 (COG4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Component Of Oligomeric Golgi Complex 4 (COG4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Component Of Oligomeric Golgi Complex 4 (COG4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Component Of Oligomeric Golgi Complex 4 (COG4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Component Of Oligomeric Golgi Complex 4 (COG4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Component Of Oligomeric Golgi Complex 4 (COG4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Component Of Oligomeric Golgi Complex 4 (COG4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Component Of Oligomeric Golgi Complex 4 (COG4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Component Of Oligomeric Golgi Complex 4 (COG4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Component Of Oligomeric Golgi Complex 4 (COG4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Component Of Oligomeric Golgi Complex 4 (COG4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Component Of Oligomeric Golgi Complex 4 (COG4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Component Of Oligomeric Golgi Complex 4 (COG4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Component Of Oligomeric Golgi Complex 4 (COG4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Component Of Oligomeric Golgi Complex 4 (COG4) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic."Dev. Cell 1:527-537(2001) [PubMed] [Europe PMC] [Abstract]
  6. "An unappreciated role for RNA surveillance."Genome Biol. 5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing."EMBO J. 28:2006-2017(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  11. "Structural basis for a human glycosylation disorder caused by mutation of the COG4 gene."Proc. Natl. Acad. Sci. U.S.A. 106:13329-13334(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Golgi function and dysfunction in the first COG4-deficient CDG type II patient."Hum. Mol. Genet. 18:3244-3256(2009) [PubMed] [Europe PMC] [Abstract]