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Chondroadherin (CHAD)

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SLRR4A; Cartilage leucine-rich protein

Chondroadherin (CHAD)
CCC J449
HGNC 1909
MGI 1096866
RGD 2336
UniProt O15335
Chondroadherin (CHAD) was initially described by Larsson et al. (1991) as a 36-kD matrix protein isolated from bovine cartilage. It was shown to mediate chondrocyte-matrix interactions. Analysis of cDNA generated from a bovine chondrocyte mRNA demonstrated that chondroadherin belongs to the family of leucine-rich repeat (LRR) proteins. Of the LRR proteins, chondroadherin is most closely related to the proteoglycans decorin, biglycan, fibromodulin, and lumican, and the matrix protein PRELP.
Each of these molecules is present in the extracellular matrix of cartilage, each possesses 10 adjacent LRR regions flanked by disulfide-bonded domains, and each possesses consensus motifs within the LRR regions for N-linked glycosylation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chondroadherin (CHAD) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chondroadherin (CHAD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chondroadherin (CHAD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chondroadherin (CHAD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chondroadherin (CHAD) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chondroadherin (CHAD) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chondroadherin (CHAD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chondroadherin (CHAD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chondroadherin (CHAD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chondroadherin (CHAD) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chondroadherin (CHAD) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chondroadherin (CHAD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chondroadherin (CHAD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chondroadherin (CHAD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chondroadherin (CHAD) ELISA Kit Customized Service Offer
  1. "The structure and chromosome location of the human chondroadherin gene (CHAD)."Genomics 45:379-385(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Association of chondroadherin with collagen type II."J. Biol. Chem. 276:32883-32888(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]