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Astrotactin 2 (ASTN2)

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Astrotactin 2 (ASTN2)
CCC J588
HGNC 17021
MGI 1889277
UniProt O75129
ASTN2 encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus.
By sequencing clones obtained from a size-fractionated human brain cDNA library, Ishikawa et al. (1998) cloned ASTN2, which they designated KIAA0634. The deduced 1,321-amino acid protein shares a high degree of similarity with mouse astrotactin (ASTN1). RT-PCR detected ASTN2 in all tissues examined, with highest expression in brain, kidney, and testis, followed by ovary.ASTN2 gene maps to chromosome 9q33.1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Astrotactin 2 (ASTN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Astrotactin 2 (ASTN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Astrotactin 2 (ASTN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Astrotactin 2 (ASTN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Astrotactin 2 (ASTN2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Astrotactin 2 (ASTN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Astrotactin 2 (ASTN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Astrotactin 2 (ASTN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Astrotactin 2 (ASTN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Astrotactin 2 (ASTN2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Astrotactin 2 (ASTN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Astrotactin 2 (ASTN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Astrotactin 2 (ASTN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Astrotactin 2 (ASTN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Astrotactin 2 (ASTN2) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 5:169-176(1998) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
  6. "Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma." Nature 469:539-542(2011) [PubMed] [Europe PMC] [Abstract]