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Actin Related Protein 2/3 Complex Subunit 5 (ARPC5)

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ARC16; p16-Arc; Arp2/3 Protein Complex Subunit p16

Actin Related Protein 2/3 Complex Subunit 5 (ARPC5)
CCC J598
HGNC 708
MGI 1915021
PubMed 22447776
RGD 1311791
UniProt O15511
Wiki ARPC5
ARPC5 encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. The ARC16 cDNA encodes a deduced 151-amino acid protein that is 26% and 21% identical to its homologs in S. pombe and S. cerevisiae, respectively.Subunits ARPC2 and ARPC4 in the core of the complex associate through long carboxy-terminal alpha helices and have similarly folded amino-terminal alpha/beta domains. ARPC1 is a 7-blade beta propeller with an insertion that may associate with the side of an actin filament. ARPC3 and ARPC5 are globular alpha-helical subunits.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ598Hu01 Recombinant Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ598Mu01 Recombinant Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Related Protein 2/3 Complex Subunit 5 (ARPC5) ELISA Kit Customized Service Offer
  1. "The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly."J. Cell Biol. 138:375-384(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins."Biochem. J. 328:105-112(1997) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]
  6. "Reconstitution of human Arp2/3 complex reveals critical roles of individual subunits in complex structure and activity."Mol. Cell 8:1041-1052(2001) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "GRAIL (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3 subunit 5 and coronin 1A."J. Biol. Chem. 286:43465-43474(2011) [PubMed] [Europe PMC] [Abstract]
  9. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]