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ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5)

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DERP11; GTRAP3-18; HSPC127; JWA; PRAF3; Addicsin; hp22; Jmx; Cytoskeleton-related vitamin A-responsive protein; Dermal papilla-derived protein 11; Prenylated Rab acceptor 2

ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5)
CCC J604
HGNC 16937
MGI 1929501
PubMed 22452940
RGD 708572
UniProt O75915
Wiki ARL6IP5
ARL6IP5 may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.Like EAAC1, GTRAP3-18 is expressed in numerous tissues. It localizes to the cell membrane and cytoplasm, and specifically interacts with the carboxy-terminal intracellular domain of EAAC1. Increasing the expression of GTRAP3-18 in cells reduces EAAC1-mediated glutamate transport by lowering substrate affinity. The expression of GTRAP3-18 can be upregulated by retinoic acid, which results in a specific reduction of EAAC1-mediated glutamate transport.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) CLIA Kit Customized Service Offer
n/a ELISA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) CLIA Kit Customized Service Offer
n/a ELISA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) CLIA Kit Customized Service Offer
n/a ELISA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) ELISA Kit Customized Service Offer
  1. "Identification of addicsin/GTRAP3-18 as a chronic morphine-augumented gene in amygdala."NeuroReport 13:2079-2084(2002) [PubMed] [Europe PMC] [Abstract]
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  3. "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells." Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
  4. "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways."Oncogene 22:3307-3318(2003) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]
  8. , Submitted (NOV-2005) to UniProtKB
  9. "Effect of differentiation inducer and heat stress on the expression of JWA protein and Hsp70 of K562 cells."Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 21:253-256(2003) [PubMed] [Europe PMC] [Abstract]
  10. "Genomic organization, expression profile, and characterization of the new protein PRA1 domain family, member 2 (PRAF2)."Gene 371:154-165(2006) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  12. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  13. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]