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ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4)

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SR-25; SRp25; SFRS20; SRp25 Nuclear Protein; Splicing Factor; Arginine/Serine-Rich 20; HSVI-binding protein; Splicing factor SRrp37

ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4)
CCC J605
HGNC 18076
MGI 1929500
PubMed 17952876
RGD 1307657
UniProt Q66PJ3
Wiki ARL6IP4
Sasahara et al. (2000) cloned novel mouse and human cDNAs, which they designated SR-25, from insulinoma cDNA libraries. The deduced human 218-amino acid protein shares 77.7% sequence identity with the mouse homolog and contains a serine-arginine (SR) repeat and 2 types of amino acid clusters: a serine cluster and a highly basic cluster. Northern blot analysis detected expression in all mouse tissues tested, with abundant expression in testis and thymus. Based on the structure and expression pattern of SR-25, Sasahara et al. (2000) suggested that the protein is localized in the nucleus and may contribute to RNA splicing. The International Radiation Hybrid Mapping Consortium mapped the ARL6IP4 gene to chromosome 12.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) CLIA Kit Customized Service Offer
n/a ELISA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) CLIA Kit Customized Service Offer
n/a ELISA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) CLIA Kit Customized Service Offer
n/a ELISA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 4 (ARL6IP4) ELISA Kit Customized Service Offer
  1. "SRrp37, a novel splicing regulator located in the nuclear speckles and nucleoli, interacts with SC35 and modulates alternative pre-mRNA splicing in vivo."J. Cell. Biochem. 108:304-314(2009) [PubMed] [Europe PMC] [Abstract]
  2. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "An SR-protein induced by HSVI binding to cells functioning as a splicing inhibitor of viral pre-mRNA."J. Mol. Biol. 316:887-894(2002) [PubMed] [Europe PMC] [Abstract]
  5. "Molecular cloning and expression analysis of a putative nuclear protein, SR-25."Biochem. Biophys. Res. Commun. 269:444-450(2000) [PubMed] [Europe PMC] [Abstract]
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Screening of human SNP database identifies recoding sites of A-to-I RNA editing."RNA 14:2074-2085(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  13. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  14. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  15. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]