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Amelogenin, X-Linked (AMELX)

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AMGX; AIH1; ALGN; AMG; AMGL; Amelogenesis Imperfecta 1

Amelogenin, X-Linked (AMELX)
CCC J645
HGNC 461
MGI 88005
PubMed 22221294
RGD 2107
UniProt Q99217
Wiki AMELX
Amelogenin, X isoform is a form of amelogenin found on the X chromosome. Amelogenin X is a member of the amelogenin family of extracellular matrix proteins. When alternative splicing occurs it results in multiple transcript variants encoding different isoforms.
Amelogenins are highly conserved proteins secreted by ameloblasts, and constitute 90% of the enamel organic matrix. As the proteins are digested and removed, the mineral crystals grow in well-organized prism patterns . The sequences were homologous to previously sequenced cDNA clones of mouse and cattle encoding amelogenin. Three exons were identified in both the X and the Y sequences.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ645Hu01 Recombinant Amelogenin, X-Linked (AMELX) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAJ645Hu01 Polyclonal Antibody to Amelogenin, X-Linked (AMELX) WB
MAJ645Hu21 Monoclonal Antibody to Amelogenin, X-Linked (AMELX) WB; IHC; ICC; IP.
Assay Kits SEJ645Hu ELISA Kit for Amelogenin, X-Linked (AMELX) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Amelogenin, X-Linked (AMELX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Amelogenin, X-Linked (AMELX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Amelogenin, X-Linked (AMELX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Amelogenin, X-Linked (AMELX) CLIA Kit Customized Service Offer
n/a ELISA Kit for Amelogenin, X-Linked (AMELX) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Amelogenin, X-Linked (AMELX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Amelogenin, X-Linked (AMELX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Amelogenin, X-Linked (AMELX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Amelogenin, X-Linked (AMELX) CLIA Kit Customized Service Offer
n/a ELISA Kit for Amelogenin, X-Linked (AMELX) ELISA Kit Customized Service Offer
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  9. "Amelogenin signal peptide mutation: correlation between mutations in the amelogenin gene (AMGX) and manifestations of X-linked amelogenesis imperfecta."Genomics 26:159-162(1995) [PubMed] [Europe PMC] [Abstract]
  10. "Characterisation of molecular defects in X-linked amelogenesis imperfecta (AIH1)."Hum. Mutat. 5:251-259(1995) [PubMed] [Europe PMC] [Abstract]
  11. "Mutational analysis of X-linked amelogenesis imperfecta in multiple families."Arch. Oral Biol. 45:79-86(2000) [PubMed] [Europe PMC] [Abstract]
  12. "An amelogenin gene defect associated with human X-linked amelogenesis imperfecta."Arch. Oral Biol. 42:235-242(1997) [PubMed] [Europe PMC] [Abstract]
  13. "Amelogenin p.M1T and p.W4S mutations underlying hypoplastic X-linked amelogenesis imperfecta."J. Dent. Res. 83:378-383(2004) [PubMed] [Europe PMC] [Abstract]