The LIM domain is a double zinc finger structure that promotes protein-protein interactions. LIM domain proteins, such as ABLIM3, play roles in embryonic development, cell lineage determination, and cancer .
RT-PCR ELISA detected highest expression in adult liver, with moderate expression in all other adult and fetal tissues examined except adult pancreas and testis, which showed little to no expression. Expression was high in cerebellum and moderate in all other adult brain regions examined.The deduced protein contains 4 LIM domains, a C-terminal VHD domain, and a putative nuclear localization signal. Mouse and human ABLIM3 share 98% amino acid identity. ABLIM3 is conserved in vertebrates, but not in invertebrates.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Actin Binding LIM Protein 3 (ABLIM3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Actin Binding LIM Protein 3 (ABLIM3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Actin Binding LIM Protein 3 (ABLIM3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Actin Binding LIM Protein 3 (ABLIM3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Actin Binding LIM Protein 3 (ABLIM3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Actin Binding LIM Protein 3 (ABLIM3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Actin Binding LIM Protein 3 (ABLIM3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Actin Binding LIM Protein 3 (ABLIM3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Actin Binding LIM Protein 3 (ABLIM3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Actin Binding LIM Protein 3 (ABLIM3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Actin Binding LIM Protein 3 (ABLIM3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Actin Binding LIM Protein 3 (ABLIM3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Actin Binding LIM Protein 3 (ABLIM3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Actin Binding LIM Protein 3 (ABLIM3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Actin Binding LIM Protein 3 (ABLIM3) | ELISA Kit Customized Service Offer |
- "Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin."J. Biol. Chem. 282:8393-8403(2007) [PubMed] [Europe PMC] [Abstract]
- "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 5:355-364(1998) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas."Oncogene 23:5901-5911(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
- "Phosphoproteome of resting human platelets."J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
- "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
- "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
- "Solution structure of the villin headpiece domain of human actin-binding LIM protein homologue (KIAA0843 protein)."Submitted (FEB-2004) to the PDB data bank