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NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5)

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CI-15k; NADH Dehydrogenase Iron-Sulfur Protein 5; NADH-ubiquinone oxidoreductase 15 kDa subunit

NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5)
CCC J795
HGNC 7712
MGI 1890889
PubMed 9763677
RGD 1311081
UniProt O43920
Wiki NDUFS5
The multisubunit NADH:ubiquinone oxidoreductase (complex I) is the first enzyme complex in the electron transport chain of mitochondria. The iron-sulfur protein (IP) fraction is made up of 7 subunits.
By a combination of EST database searching and RT-PCR, Loeffen et al. (1999) isolated cDNAs encoding the human homolog of the bovine 15-kD IP subunit. The predicted 106-amino acid human NDUFS5 protein shares 75% homology with the bovine protein. Northern dot blot analysis revealed that NDUFS5 was expressed in all human tissues tested. Mao et al. (1998) identified an NDUFS5 cDNA, HD-CI-15, among a collection of cDNAs expressed in hematopoietic stem/progenitor cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) CLIA Kit Customized Service Offer
n/a ELISA Kit for NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) CLIA Kit Customized Service Offer
n/a ELISA Kit for NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) CLIA Kit Customized Service Offer
n/a ELISA Kit for NADH Dehydrogenase Ubiquinone Fe-S Protein 5 (NDUFS5) ELISA Kit Customized Service Offer
  1. "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning."Proc. Natl. Acad. Sci. U.S.A. 95:8175-8180(1998) [PubMed] [Europe PMC] [Abstract]
  2. "The human NADH:ubiquinone oxidoreductase NDUFS5 (15 kDa) subunit: cDNA cloning, chromosomal localization, tissue distribution and the absence of mutations in isolated complex I-deficient patients."J. Inherit. Metab. Dis. 22:19-28(1999) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification."J. Biol. Chem. 278:13619-13622(2003) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "NDUFB7 and NDUFA8 are located at the intermembrane surface of complex I."FEBS Lett. 585:737-743(2011) [PubMed] [Europe PMC] [Abstract]
  7. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  9. "High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency."Nat. Genet. 42:851-858(2010) [PubMed] [Europe PMC] [Abstract]