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Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Kinase Gamma (IkBKg)

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IP; FIP-3; FIP3; Fip3p; IKK-gamma; IP1; IP2; NEMO; NF-Kappa-B Essential Modulator; Incontinentia Pigmenti; IkB kinase-associated protein 1; NF-kappa-B essential modifier

Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Kinase Gamma (IkBKg)
CCC J820
HGNC 5961
MGI 1338074
PubMed 19656162
RGD 735223
UniProt Q9Y6K9
Wiki IKBKG
IKBKg encodes the regulatory subunit of the inhibitor of kappaB kinase complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.The 2.8-kb NEMO cDNA encodes a 412-amino acid protein that is acidic, rich in glutamic acid and glutamine residues, and contains a leucine zipper motif at amino acids 315-342. NEMO also complemented the 1.3E2 mutant cell line, in which NFKB is not activated in response to a large set of stimuli.

Organism species: Homo sapiens (Human)

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Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Kinase Gamma (IkBKg) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Kinase Gamma (IkBKg) Monoclonal Antibody Customized Service Offer
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Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Kinase Gamma (IkBKg) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Kinase Gamma (IkBKg) Monoclonal Antibody Customized Service Offer
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