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Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1)

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GRB1; p85-ALPHA; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha

Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1)
CCC J833
HGNC 8979
MGI 97583
PubMed 21478295
RGD 3329
UniProt P27986
Wiki PIK3R1
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD.
PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in three transcript variants encoding different isoforms.The 2 subunits shared 62% amino acid sequence identity across their entire length. Both sequences contained an N-terminal SH3 region, 2 SH2 regions, and a region of homology to the C-terminal region of BCR.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1) ELISA Kit Customized Service Offer
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