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Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5)

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GEF5; P60; TIM; TIM1; Ephexin-3; Transforming Immortalized Mammary Oncogene; Guanine Nucleotide Regulatory Protein TIM

Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5)
CCC J857
HGNC 13209
MGI 1858952
PubMed 21525037
UniProt Q12774
Wiki ARHGEF5
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. ARHGEF5 may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.
The 2.3-kb TIM cDNA encodes a predicted protein of 60-kD containing a Dbl-homology (DH) domain. The DH motif is shared by several signal transducing molecules that are implicated as regulators of small GTP-binding proteins. Therefore, the TIM oncogene is also thought to be involved in the control of cytoskeletal organization through regulation of small GTP-binding proteins.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5) ELISA Kit Customized Service Offer
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  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]