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HIRA Interacting Protein 3 (HIRIP3)

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HIRA Interacting Protein 3 (HIRIP3)
CCC K124
HGNC 4917
MGI 2142364
PubMed 17391060
RGD 1306463
UniProt Q9BW71
Wiki HIRIP3
The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Recently, several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the HIRIP3 gene product binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism.
The predicted partial protein sequence of HIRIP3 contained 20% acidic and 21% basic amino acids, including several stretches of lysine and arginine residues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant HIRA Interacting Protein 3 (HIRIP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to HIRA Interacting Protein 3 (HIRIP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to HIRA Interacting Protein 3 (HIRIP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for HIRA Interacting Protein 3 (HIRIP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for HIRA Interacting Protein 3 (HIRIP3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant HIRA Interacting Protein 3 (HIRIP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to HIRA Interacting Protein 3 (HIRIP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to HIRA Interacting Protein 3 (HIRIP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for HIRA Interacting Protein 3 (HIRIP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for HIRA Interacting Protein 3 (HIRIP3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant HIRA Interacting Protein 3 (HIRIP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to HIRA Interacting Protein 3 (HIRIP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to HIRA Interacting Protein 3 (HIRIP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for HIRA Interacting Protein 3 (HIRIP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for HIRA Interacting Protein 3 (HIRIP3) ELISA Kit Customized Service Offer
  1. "Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA."Mol. Cell. Biol. 18:5546-5556(1998) [PubMed] [Europe PMC] [Abstract]
  2. "HIRIP3 is a nuclear phosphoprotein interacting with and phosphorylated by the serine-threonine kinase CK2."Biol. Chem. 388:391-398(2007) [PubMed] [Europe PMC] [Abstract]
  3. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  6. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment."J. Proteome Res. 7:5167-5176(2008) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]