DNAJB8 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain .
By searching EST databases for J domain-containing proteins, Ohtsuka and Hata (2000) identified 10 mouse and human DNAJ homologs, including mouse Dnajb8. The predicted type II transmembrane protein contains 227 amino acids with an N-terminal J domain.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 8 (DNAJB8) | ELISA Kit Customized Service Offer |
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation."Mol. Cell 37:355-369(2010) [PubMed] [Europe PMC] [Abstract]
- "Solution structure of the J domain of DnaJ homolog subfamily B member 8."Submitted (OCT-2006) to the PDB data bank