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DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11)

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ABBP2; EDJ; ERdj3; ERj3; HEDJ; hDj9; APOBEC1-binding protein 2; ER-associated Hsp40 co-chaperone; Endoplasmic reticulum DNA J domain-containing 3; PWP1-interacting 4

DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11)
CCC K131
HGNC 14889
MGI 1915088
PubMed 21673190
RGD 1307373
UniProt Q9UBS4
Wiki DNAJB11
DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a C-terminal cysteine-rich region.The deduced 358-amino acid protein has a calculated molecular mass of 40.5 kD and shares 99% sequence identity with the mouse protein. DNAJB11 contains a conserved J domain, a weak G/F region, and a region that contains 4 cysteines but lacks the zinc finger domain found in some DNAJ proteins. The secondary and tertiary structures of DNAJB11 closely resemble those of HDJ1 (DNAJB1). Northern blot analysis detected transcripts of 1.5 and 2.0 kb in all tissues examined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) Polyclonal Antibody Customized Service Offer
Assay Kits SEK131Hu ELISA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) CLIA Kit Customized Service Offer
n/a ELISA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) CLIA Kit Customized Service Offer
n/a ELISA Kit for DnaJ/HSP40 Homolog Subfamily B, Member 11 (DNAJB11) ELISA Kit Customized Service Offer
  1. "Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature."Cell Stress Chaperones 5:98-112(2000) [PubMed] [Europe PMC] [Abstract]
  2. "HEDJ, an Hsp40 co-chaperone localized to the endoplasmic reticulum of human cells."J. Biol. Chem. 275:24984-24992(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Characterization of pancreatic ERj3p, a homolog of yeast DnaJ-like protein Scj1p."Biol. Chem. 385:389-395(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  5. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "A DnaJ protein, apobec-1-binding protein-2, modulates apolipoprotein B mRNA editing."J. Biol. Chem. 276:46445-46452(2001) [PubMed] [Europe PMC] [Abstract]
  8. "A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins."Mol. Biol. Cell 13:4456-4469(2002) [PubMed] [Europe PMC] [Abstract]
  9. "Localization and function in endoplasmic reticulum stress tolerance of ERdj3, a new member of Hsp40 family protein."Cell Stress Chaperones 9:253-264(2004) [PubMed] [Europe PMC] [Abstract]
  10. "ERdj3, a stress-inducible endoplasmic reticulum DnaJ homologue, serves as a cofactor for BiP's interactions with unfolded substrates."Mol. Biol. Cell 16:40-50(2005) [PubMed] [Europe PMC] [Abstract]
  11. "Contribution of the HEDJ/ERdj3 cysteine-rich domain to substrate interactions."Arch. Biochem. Biophys. 468:147-158(2007) [PubMed] [Europe PMC] [Abstract]
  12. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  13. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  15. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]