≡

DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3)

[Edit]

TID1; hTid-1; HCA57; Hepatocellular carcinoma-associated antigen 57; Tumorous imaginal discs protein Tid56 homolog

DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3)
CCC K143
HGNC 11808
MGI 1933786
PubMed 22595283
RGD 1306527
UniProt Q96EY1
Wiki DNAJA3
DNAJA3 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins. For background information on the DNAJ family. TID1 binds via its J domain to the C terminus of the oncogenic HPV-16 E7 more efficiently than to the 'low-risk' HPV-6 E7.
The predicted 480-amino acid DNAJA3 protein contains a J domain, as well as other conserved regions found in some DNAJ proteins, including a glycine/phenylalanine-rich region and a cysteine-rich region. Northern blot analysis revealed wide expression of a 2.7-kb transcript, with highest levels in heart, liver, and skeletal muscle. DNAJA3 was also expressed in foreskin keratinocytes, the normal host cells of HPVs, and in the HPV-positive HeLa cell line.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) CLIA Kit Customized Service Offer
n/a ELISA Kit for DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) CLIA Kit Customized Service Offer
n/a ELISA Kit for DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) CLIA Kit Customized Service Offer
n/a ELISA Kit for DnaJ/HSP40 Homolog Subfamily A, Member 3 (DNAJA3) ELISA Kit Customized Service Offer
  1. "A novel human DnaJ protein, hTid-1, a homolog of the Drosophila tumor suppressor protein Tid56, can interact with the human papillomavirus type 16 E7 oncoprotein."Virology 247:74-85(1998) [PubMed] [Europe PMC] [Abstract]
  2. "hTid-1, a human DnaJ protein, modulates the interferon signaling pathway."J. Biol. Chem. 276:49034-49042(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies."J. Immunol. 169:1102-1109(2002) [PubMed] [Europe PMC] [Abstract]
  7. "TID1, a human homolog of the Drosophila tumor suppressor l(2)tid, encodes two mitochondrial modulators of apoptosis with opposing functions."Proc. Natl. Acad. Sci. U.S.A. 96:8499-8504(1999) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "A Y2H-seq approach defines the human protein methyltransferase interactome."Nat. Methods 10:339-342(2013) [PubMed] [Europe PMC] [Abstract]
  10. "Solution structure of J-domain and of zinc finger domain from human DnaJ subfamily A member 3."Submitted (OCT-2006) to the PDB data bank