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C1q And Tumor Necrosis Factor Related Protein 5 (C1QTNF5)

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CTRP5; LORD

C1q And Tumor Necrosis Factor Related Protein 5 (C1QTNF5)
CCC K171
HGNC 14344
MGI 2385958
PubMed 24531000
UniProt Q9BXJ0
Wiki C1QTNF5
The CTRP5 protein is a member of the C1q / tumor necrosis factor superfamily, which shows diverse functions including cell adhesion and as components of the basement membrane. C1QTNF5 is mutant in late-onset retinal degeneration.
CTRP5 gene consists of 3 exons that generate a 1.8-kb transcript. It is contained within the 3-prime untranslated region of exon 13 of the MFRP gene. CTRP5 is present in the same orientation as MFRP, and both genes are expressed as a bicistronic transcript.CTRP5 and MFRP interact directly in a yeast 2-hybrid system. Other observations suggested that CTRP5 is secreted by the RPE and is a constituent of the Bruch membrane.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPK171Hu01 Recombinant C1q And Tumor Necrosis Factor Related Protein 5 (C1QTNF5) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to C1q And Tumor Necrosis Factor Related Protein 5 (C1QTNF5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C1q And Tumor Necrosis Factor Related Protein 5 (C1QTNF5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C1q And Tumor Necrosis Factor Related Protein 5 (C1QTNF5) CLIA Kit Customized Service Offer
n/a ELISA Kit for C1q And Tumor Necrosis Factor Related Protein 5 (C1QTNF5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C1q And Tumor Necrosis Factor Related Protein 5 (C1QTNF5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C1q And Tumor Necrosis Factor Related Protein 5 (C1QTNF5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C1q And Tumor Necrosis Factor Related Protein 5 (C1QTNF5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C1q And Tumor Necrosis Factor Related Protein 5 (C1QTNF5) CLIA Kit Customized Service Offer
n/a ELISA Kit for C1q And Tumor Necrosis Factor Related Protein 5 (C1QTNF5) ELISA Kit Customized Service Offer
  1. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Crystal structure of the globular domain of C1QTNF5: Implications for late-onset retinal macular degeneration."J. Struct. Biol. 180:439-446(2012) [PubMed] [Europe PMC] [Abstract]
  7. "Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration."Hum. Mol. Genet. 12:2657-2667(2003) [PubMed] [Europe PMC] [Abstract]