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Bcl2/Adenovirus E1B 19kDa Interacting Protein Like Protein (BNIPL)

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BNIP-S; BNIPL1; BNIPL2; PP753

Bcl2/Adenovirus E1B 19kDa Interacting Protein Like Protein (BNIPL)
CCC K175
HGNC 16976
MGI 2384749
PubMed 16143817
UniProt Q7Z465
Wiki BNIPL
The BNIPS-alpha isoform shared 46% identity with BNIP2 with higher similarity over the BCH domain, which is predicted to comprise several alpha helices. PCR analysis detected differing levels of expression of the BNIPS-alpha and BNIPS-beta isoforms in a number of human cancer cell lines including breast cancer MCF-7, HeLa cells, 293T embryonic transformed kidney epithelial cells, and stomach and colon cancer cell lines. PCR analysis of mouse tissues detected expression of BNIPS-alpha in all tissues examined.
Immunofluorescence studies localized the BNIPS-alpha isoform to the cytosol and BNIPS-beta primarily to the nucleus. overexpression of BNIPL inhibited cell growth in human hepatocarcinoma cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bcl2/Adenovirus E1B 19kDa Interacting Protein Like Protein (BNIPL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bcl2/Adenovirus E1B 19kDa Interacting Protein Like Protein (BNIPL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bcl2/Adenovirus E1B 19kDa Interacting Protein Like Protein (BNIPL) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bcl2/Adenovirus E1B 19kDa Interacting Protein Like Protein (BNIPL) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bcl2/Adenovirus E1B 19kDa Interacting Protein Like Protein (BNIPL) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bcl2/Adenovirus E1B 19kDa Interacting Protein Like Protein (BNIPL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bcl2/Adenovirus E1B 19kDa Interacting Protein Like Protein (BNIPL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bcl2/Adenovirus E1B 19kDa Interacting Protein Like Protein (BNIPL) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bcl2/Adenovirus E1B 19kDa Interacting Protein Like Protein (BNIPL) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bcl2/Adenovirus E1B 19kDa Interacting Protein Like Protein (BNIPL) ELISA Kit Customized Service Offer
  1. "The BNIP-2 and Cdc42GAP homology/Sec14p-like domain of BNIP-Salpha is a novel apoptosis-inducing sequence."J. Biol. Chem. 277:7483-7492(2002) [PubMed] [Europe PMC] [Abstract]
  2. "BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis."Biochem. Biophys. Res. Commun. 308:379-385(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The apoptosis-associated protein BNIPL interacts with two cell proliferation-related proteins, MIF and GFER."FEBS Lett. 540:86-90(2003) [PubMed] [Europe PMC] [Abstract]