≡

Abl Interactor 3 (ABI3)

[Edit]

NESH; SSH3BP3; New molecule including SH3

Abl Interactor 3 (ABI3)
CCC K183
HGNC 29859
MGI 1913860
PubMed 16463099
RGD 1311794
UniProt Q9P2A4
Wiki ABI3
ABI3 encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase.
SH3 domains contain about 50 amino acids that bind to proline-rich sequences and often play a role in cell growth signaling. Sequence analysis predicted that the 366-amino acid NESH protein, which is most homologous to SSH3BP1, has a central serine-rich region followed by a proline-rich region and a C-terminal SH3 domain. RT-PCR analysis detected variable expression of NESH in all tissues tested.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Abl Interactor 3 (ABI3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Abl Interactor 3 (ABI3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Abl Interactor 3 (ABI3) Polyclonal Antibody Customized Service Offer
Assay Kits SEK183Hu ELISA Kit for Abl Interactor 3 (ABI3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Abl Interactor 3 (ABI3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Abl Interactor 3 (ABI3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Abl Interactor 3 (ABI3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Abl Interactor 3 (ABI3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Abl Interactor 3 (ABI3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Abl Interactor 3 (ABI3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Abl Interactor 3 (ABI3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Abl Interactor 3 (ABI3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Abl Interactor 3 (ABI3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Abl Interactor 3 (ABI3) ELISA Kit Customized Service Offer
  1. "Isolation and characterization of a novel human gene (NESH) which encodes a putative signaling molecule similar to e3B1 protein."Biochim. Biophys. Acta 1493:237-241(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells."Cancer Res. 62:2215-2219(2002) [PubMed] [Europe PMC] [Abstract]
  6. "Cloning and sequencing of a novel human gene that encodes a putative target protein of Nesh-SH3."J. Hum. Genet. 46:483-486(2001) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]