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A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10)

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WMS; ADAM-TS10

A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10)
CCC K210
HGNC 13201
MGI 2449112
PubMed 21402694
UniProt Q9H324
Wiki ADAMTS10
ADAMTS10 belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration.
The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPK210Hu01 Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAK210Hu01 Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) WB; IHC; ICC; IP.
LAK210Hu71 Biotin-Linked Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) WB; IHC; ICC.
Assay Kits SEK210Hu ELISA Kit for A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) CLIA Kit Customized Service Offer
n/a ELISA Kit for A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPK210Ra01 Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAK210Ra01 Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) CLIA Kit Customized Service Offer
n/a ELISA Kit for A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) ELISA Kit Customized Service Offer
  1. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Discovery and characterization of a novel, widely expressed metalloprotease, ADAMTS10, and its proteolytic activation."J. Biol. Chem. 279:51208-51217(2004) [PubMed] [Europe PMC] [Abstract]
  3. "ADAMTS10 mutations in autosomal recessive Weill-Marchesani syndrome."Am. J. Hum. Genet. 75:801-806(2004) [PubMed] [Europe PMC] [Abstract]
  4. "ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts."J. Biol. Chem. 286:17156-17167(2011) [PubMed] [Europe PMC] [Abstract]
  5. "Functional analysis of an ADAMTS10 signal peptide mutation in Weill-Marchesani syndrome demonstrates a long-range effect on secretion of the full-length enzyme."Hum. Mutat. 29:1425-1434(2008) [PubMed] [Europe PMC] [Abstract]