≡

RAB3A, Member RAS Oncogene Family (RAB3A)

[Edit]

RAB3A, Member RAS Oncogene Family (RAB3A)
CCC K303
HGNC 9777
MGI 97843
PubMed 2687157
RGD 3528
UniProt P20336
Wiki RAB3A
The RAS gene superfamily is divided into 3 main branches according to protein homology. In mammals the first branch includes the classic RAS genes as well as RAL and RRAS. The RHO genes belong to the second branch and the RAB genes to the third. The RAB genes were so named because they were first isolated from a rat brain library. The predicted 220-amino acid human RAB3A protein shares 99% and 78% identity with rat Rab3A and human RAB3B, respectively.
Synapsin I stimulated the Rab3a cycle by increasing GTP binding, GTPase activity, and Rab3a recruitment to the synaptic vesicle membrane. Conversely, Rab3a inhibited synapsin I binding to actin and synapsin I-induced synaptic vesicle clustering.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB3A, Member RAS Oncogene Family (RAB3A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB3A, Member RAS Oncogene Family (RAB3A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB3A, Member RAS Oncogene Family (RAB3A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB3A, Member RAS Oncogene Family (RAB3A) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB3A, Member RAS Oncogene Family (RAB3A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB3A, Member RAS Oncogene Family (RAB3A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB3A, Member RAS Oncogene Family (RAB3A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB3A, Member RAS Oncogene Family (RAB3A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB3A, Member RAS Oncogene Family (RAB3A) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB3A, Member RAS Oncogene Family (RAB3A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB3A, Member RAS Oncogene Family (RAB3A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB3A, Member RAS Oncogene Family (RAB3A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB3A, Member RAS Oncogene Family (RAB3A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB3A, Member RAS Oncogene Family (RAB3A) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB3A, Member RAS Oncogene Family (RAB3A) ELISA Kit Customized Service Offer
  1. "The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion."J. Biol. Chem. 264:12394-12401(1989) [PubMed] [Europe PMC] [Abstract]
  2. "Genomic organisation of the human cyclic AMP-specific phosphodiesterase PDE4C gene and its chromosomal localisation to 19p13.1, between RAB3A and JUND."Cell. Signal. 11:735-742(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Isoprenoid modification of rab proteins terminating in CC or CXC motifs."Proc. Natl. Acad. Sci. U.S.A. 88:6264-6268(1991) [PubMed] [Europe PMC] [Abstract]
  7. "Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A."Proc. Natl. Acad. Sci. U.S.A. 91:11963-11967(1994) [PubMed] [Europe PMC] [Abstract]