Family With Sequence Similarity 20, Member B (FAM20B)

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Xylose kinase; Glycosaminoglycan xylosylkinase

Family With Sequence Similarity 20, Member B (FAM20B)
Using representational difference analysis to identify genes that are differentially expressed during experimentally induced myeloid differentiation in the mouse EML hematopoietic stem cell line, By database analysis with the mouse Fam20a sequence as query, Nalbant et al. (2005) identified a family of genes with related sequence that included 2 additional members in mammals, FAM20B and FAM20C . The 3 deduced proteins are highly conserved in human, mouse, and rat. All contain a conserved putative signal sequence and a conserved C-terminal sequence. The deduced human FAM20B protein contains 459 amino acids. Expression analysis showed that, like FAM20A, FAM20B and FAM20C are expressed during hematopoiesis.The International Radiation Hybrid Mapping Consortium mapped the FAM20B gene to chromosome 1 .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 20, Member B (FAM20B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 20, Member B (FAM20B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 20, Member B (FAM20B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 20, Member B (FAM20B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 20, Member B (FAM20B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 20, Member B (FAM20B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 20, Member B (FAM20B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 20, Member B (FAM20B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 20, Member B (FAM20B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 20, Member B (FAM20B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 20, Member B (FAM20B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 20, Member B (FAM20B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 20, Member B (FAM20B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 20, Member B (FAM20B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 20, Member B (FAM20B) ELISA Kit Customized Service Offer
  1. "FAM20B is a kinase that phosphorylates xylose in the glycosaminoglycan-protein linkage region."Biochem. J. 421:157-162(2009) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain."DNA Res. 4:345-349(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cells."BMC Genomics 6:11-11(2005) [PubMed] [Europe PMC] [Abstract]
  7. "2-o-phosphorylation of xylose and 6-O-sulfation of galactose in the protein linkage region of glycosaminoglycans influence the glucuronyltransferase-I activity involved in the linkage region synthesis."J. Biol. Chem. 283:16801-16807(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Identification of phosphatase that dephosphorylates xylose in the glycosaminoglycan-protein linkage region of proteoglycans."J. Biol. Chem. 289:6695-6708(2014) [PubMed] [Europe PMC] [Abstract]