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Family With Sequence Similarity 9, Member B (FAM9B)

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Family With Sequence Similarity 9, Member B (FAM9B)
CCC K375
HGNC 18404
PubMed 12213195
UniProt Q8IZU0
By characterizing a region of chromosome Xp22 involved in a translocation with chromosome 10, followed by EST database analysis and 5-prime RACE of a testis cDNA library, Martinez-Garay et al. (2002) cloned full-length FAM9B. The deduced 186-amino acid protein contains 3 overlapping putative bipartite nuclear localization signals.
FAM9B shares 65% amino acid identity with FAM9C), 46% identity with FAM9A , and about 30% identity with rodent Sycp3. Northern blot analysis of several tissues detected expression only in testis. Fluorescence-tagged FAM9B localized to the nucleus of transfected COS-7 cells. There was also faint cytoplasmic staining.Martinez-Garay et al. (2002) determined that the FAM9B gene contains 9 exons and spans about 9 kb.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 9, Member B (FAM9B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 9, Member B (FAM9B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 9, Member B (FAM9B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 9, Member B (FAM9B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 9, Member B (FAM9B) ELISA Kit Customized Service Offer
  1. "A new gene family (FAM9) of low-copy repeats in Xp22.3 expressed exclusively in testis: implications for recombinations in this region."Genomics 80:259-267(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]