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Unc-80 Homolog (UNC80)

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C2orf21

Unc-80 Homolog (UNC80)
CCC K474
HGNC 26582
UniProt Q8N2C7
Unc80 was required for proper localization or stabilization of axonal NCA ion channel components, which are homologous to the vertebrate NALCN channel.The activation of substance P through its G protein-coupled receptor TACR1 occurs by means of a unique mechanism: it does not require G protein activation but is dependent on Src family kinases.
The deduced protein contains 1,341 amino acids. RT-PCR ELISA detected C2ORF21 expression in adult and fetal brain and in all specific adult brain regions examined. Very low expression was detected in testis and pancreas, and no expression was detected in other adult and fetal tissues examined.The deduced protein contains 3,184 amino acids. Fluorescence-tagged Unc80 was highly expressed throughout the worm nervous system, as well as in other tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Unc-80 Homolog (UNC80) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Unc-80 Homolog (UNC80) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Unc-80 Homolog (UNC80) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Unc-80 Homolog (UNC80) CLIA Kit Customized Service Offer
n/a ELISA Kit for Unc-80 Homolog (UNC80) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 8:85-95(2001) [PubMed] [Europe PMC] [Abstract]
  5. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]