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Alpha And Gamma-Adaptin Binding Protein (aAgAB)

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P34

Alpha And Gamma-Adaptin Binding Protein (aAgAB)
CCC K498
HGNC 25662
MGI 1914189
PubMed 23064416
RGD 621601
UniProt Q6PD74
AAGAB May play a role in membrane traffic. Interacts with AP1G1 and AP2A1. Adaptins are proteins mediating the formation of clathrin-coated pits, through interaction with membrane-bound receptors. There are several types of adaptin, each related to a different group of such receptors.Adaptins show sequence similarity to some COPI subunits, thus they are thought to have a common evolutionary origin.Adaptins cluster to form the AP2 complex. cDNA Sources:brain; intestine; muscle; cervix; stomach; thymus; testis; prostate; connective tissue; kidney; lung; embryonic tissue; uncharacterized tissue; ovary; skin; mixed; liver; eye; pituitary gland; mammary gland; placenta; uterus; pharynx; blood; pancreas; mouth; bone marrow; adipose tissue; esophagus; heart; bone; thyroid; bladder; parathyroid; vascular; spleen; ascites; umbilical cord; adrenal gland; pineal gland; lymph node

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPK498Hu01 Recombinant Alpha And Gamma-Adaptin Binding Protein (aAgAB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Alpha And Gamma-Adaptin Binding Protein (aAgAB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Alpha And Gamma-Adaptin Binding Protein (aAgAB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Alpha And Gamma-Adaptin Binding Protein (aAgAB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Alpha And Gamma-Adaptin Binding Protein (aAgAB) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Alpha And Gamma-Adaptin Binding Protein (aAgAB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Alpha And Gamma-Adaptin Binding Protein (aAgAB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Alpha And Gamma-Adaptin Binding Protein (aAgAB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Alpha And Gamma-Adaptin Binding Protein (aAgAB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Alpha And Gamma-Adaptin Binding Protein (aAgAB) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Alpha And Gamma-Adaptin Binding Protein (aAgAB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Alpha And Gamma-Adaptin Binding Protein (aAgAB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Alpha And Gamma-Adaptin Binding Protein (aAgAB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Alpha And Gamma-Adaptin Binding Protein (aAgAB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Alpha And Gamma-Adaptin Binding Protein (aAgAB) ELISA Kit Customized Service Offer
  1. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  10. "Nonsense mutations in AAGAB cause punctate palmoplantar keratoderma type Buschke-Fischer-Brauer."Am. J. Hum. Genet. 91:754-759(2012) [PubMed] [Europe PMC] [Abstract]
  11. "Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma." Nat. Genet. 44:1272-1276(2012) [PubMed] [Europe PMC] [Abstract]