Lufenuron (Luf)

Lufenuron is the active ingredient in the veterinary flea control medication Program, and one of the active ingredients in the veterinary flea control, heartworm prevention, and anthelmintic medicine milbemycin oxime/lufenuron. Lufenuron is stored in the animal's body fat and transferred to adult fleas through their bites. Adult fleas transfer it to their eggs by its presence in the female flea's blood, or by the larvae feeding on predigested blood. Lufenuron, a benzoylurea pesticide, inhibits the production of chitin in larval fleas. Without chitin, a larval flea will never develop an exoskeleton. Attacking the ability to create chitin may make lufenuron a remedy against fungal infections, such as ringworm.It has no known toxic effects at any dosage on humans or other animals in the environment that do not depend on chitin, though the orally administered pills can sometimes cause an upset stomach with acid reflux.