GTP Binding Protein 5 (GTPBP5)
[Edit]ObgH1; MTG2; Protein obg homolog 1; Mitochondrial ribosome-associated GTPase 2
Small G proteins, such as GTPBP5, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction.By searching human databases for homologs of Escherichia coli Obg proteins, Hirano et al. (2006) identified GTPBP5, which they called OBGH1. The deduced 406-amino acid protein contains an N-terminal mitochondria-localization signal, followed by a glycine-rich region, and a GTPase domain with 5 characteristic subdomains. Epitope-tagged GTPBP5 localized to mitochondria.Hirano et al. (2006) demonstrated that recombinant GTPBP5 showed GTPase activity in vitro. RNA interference of GTPBP5 in HeLa cells resulted in elongated mitochondria and abnormal nuclear morphologies.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant GTP Binding Protein 5 (GTPBP5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to GTP Binding Protein 5 (GTPBP5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to GTP Binding Protein 5 (GTPBP5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for GTP Binding Protein 5 (GTPBP5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for GTP Binding Protein 5 (GTPBP5) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant GTP Binding Protein 5 (GTPBP5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to GTP Binding Protein 5 (GTPBP5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to GTP Binding Protein 5 (GTPBP5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for GTP Binding Protein 5 (GTPBP5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for GTP Binding Protein 5 (GTPBP5) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant GTP Binding Protein 5 (GTPBP5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to GTP Binding Protein 5 (GTPBP5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to GTP Binding Protein 5 (GTPBP5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for GTP Binding Protein 5 (GTPBP5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for GTP Binding Protein 5 (GTPBP5) | ELISA Kit Customized Service Offer |
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- "Human small G proteins, ObgH1, and ObgH2, participate in the maintenance of mitochondria and nucleolar architectures."Genes Cells 11:1295-1304(2006) [PubMed] [Europe PMC] [Abstract]
- "Human G-proteins, ObgH1 and Mtg1, associate with the large mitochondrial ribosome subunit and are involved in translation and assembly of respiratory complexes."Nucleic Acids Res. 41:3713-3722(2013) [PubMed] [Europe PMC] [Abstract]