≡

Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1)

[Edit]

FGFR5; FHFR; FGF homologous factor receptor; FGFR-like protein; Fibroblast growth factor receptor 5

Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1)
CCC L113
HGNC 3693
MGI 2150920
PubMed 22432025
RGD 735156
UniProt Q8N441
Wiki FGFRL1
FGFRL1 is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL113Hu01 Recombinant Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAL113Hu01 Polyclonal Antibody to Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) WB; IHC; ICC; IP.
MAL113Hu21 Monoclonal Antibody to Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) WB; IHC; ICC; IP.
Assay Kits SEL113Hu ELISA Kit for Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL113Mu01 Recombinant Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAL113Mu01 Polyclonal Antibody to Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL113Ra01 Recombinant Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAL113Ra01 Polyclonal Antibody to Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) ELISA Kit Customized Service Offer
  1. "Characterization of a novel protein (FGFRL1) from human cartilage related to FGF receptors."Genomics 69:275-279(2000) [PubMed] [Europe PMC] [Abstract]
  2. "A novel fibroblast growth factor receptor-5 preferentially expressed in the pancreas."Biochim. Biophys. Acta 1518:152-156(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Identification of a new fibroblast growth factor receptor, FGFR5."Gene 271:171-182(2001) [PubMed] [Europe PMC] [Abstract]
  8. "Characterization of FGFRL1, a novel fibroblast growth factor (FGF) receptor preferentially expressed in skeletal tissues."J. Biol. Chem. 278:33857-33865(2003) [PubMed] [Europe PMC] [Abstract]