Anaphase Promoting Complex Subunit 5 (ANAPC5)

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APC5; PDL-108; Cyclosome subunit 5

Anaphase Promoting Complex Subunit 5 (ANAPC5)
ANAPC5 encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Anaphase Promoting Complex Subunit 5 (ANAPC5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Anaphase Promoting Complex Subunit 5 (ANAPC5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Anaphase Promoting Complex Subunit 5 (ANAPC5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Anaphase Promoting Complex Subunit 5 (ANAPC5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Anaphase Promoting Complex Subunit 5 (ANAPC5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Anaphase Promoting Complex Subunit 5 (ANAPC5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Anaphase Promoting Complex Subunit 5 (ANAPC5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Anaphase Promoting Complex Subunit 5 (ANAPC5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Anaphase Promoting Complex Subunit 5 (ANAPC5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Anaphase Promoting Complex Subunit 5 (ANAPC5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Anaphase Promoting Complex Subunit 5 (ANAPC5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Anaphase Promoting Complex Subunit 5 (ANAPC5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Anaphase Promoting Complex Subunit 5 (ANAPC5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Anaphase Promoting Complex Subunit 5 (ANAPC5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Anaphase Promoting Complex Subunit 5 (ANAPC5) ELISA Kit Customized Service Offer
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