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Rho GTPase Activating Protein 24 (ARHGAP24)

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FILGAP; RC-GAP72; RCGAP72; p73; p73RhoGAP; Filamin-A-associated RhoGAP; RAC1- and CDC42-specific GTPase-activating protein of 72 kDa; Sarcoma antigen NY-SAR-88

Rho GTPase Activating Protein 24 (ARHGAP24)
CCC L209
HGNC 25361
MGI 1922647
PubMed 21911940
RGD 1306669
UniProt Q8N264
Wiki ARHGAP24
The predicted p73 protein contains 655 amino acids and has a calculated molecular mass of 73 kD. The deduced 655-amino acid protein has a calculated molecular mass of 72 kD and shares 87% amino acid identity its mouse homolog. Northern blot analysis detected variable expression of Rcgap72 in all mouse tissues examined, with highest expression in kidney. Northern and Western blot analyses of several human cell lines detected RCGAP72 expression in HeLa cells and a nonsmall cell lung carcinoma cell line only. Western blot analysis of HeLa cells revealed an 80-kD RCGAP72 protein. Immunofluorescence microscopy of transfected mouse fibroblasts showed fluorescence-tagged RCGAP72 associated with actin stress fibers. In

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho GTPase Activating Protein 24 (ARHGAP24) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho GTPase Activating Protein 24 (ARHGAP24) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho GTPase Activating Protein 24 (ARHGAP24) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho GTPase Activating Protein 24 (ARHGAP24) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho GTPase Activating Protein 24 (ARHGAP24) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho GTPase Activating Protein 24 (ARHGAP24) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho GTPase Activating Protein 24 (ARHGAP24) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho GTPase Activating Protein 24 (ARHGAP24) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho GTPase Activating Protein 24 (ARHGAP24) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho GTPase Activating Protein 24 (ARHGAP24) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho GTPase Activating Protein 24 (ARHGAP24) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho GTPase Activating Protein 24 (ARHGAP24) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho GTPase Activating Protein 24 (ARHGAP24) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho GTPase Activating Protein 24 (ARHGAP24) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho GTPase Activating Protein 24 (ARHGAP24) ELISA Kit Customized Service Offer
  1. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Immunomic analysis of human sarcoma."Proc. Natl. Acad. Sci. U.S.A. 100:2651-2656(2003) [PubMed] [Europe PMC] [Abstract]
  5. "Identification and characterization of ARHGAP24 and ARHGAP25 genes in silico."Int. J. Mol. Med. 14:333-338(2004) [PubMed] [Europe PMC] [Abstract]
  6. "A vascular cell-restricted RhoGAP, p73RhoGAP, is a key regulator of angiogenesis."Proc. Natl. Acad. Sci. U.S.A. 101:12212-12217(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Characterization of a novel GTPase-activating protein associated with focal adhesions and the actin cytoskeleton."J. Biol. Chem. 280:7178-7185(2005) [PubMed] [Europe PMC] [Abstract]
  8. "FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling."Nat. Cell Biol. 8:803-814(2006) [PubMed] [Europe PMC] [Abstract]