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Calcium Binding And Coiled Coil Domain Containing Protein 2 (CALCOCO2)

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NDP52; Nuclear dot protein 52; Nuclear domain 10 protein NDP52; Antigen nuclear dot 52 kDa protein

Calcium Binding And Coiled Coil Domain Containing Protein 2 (CALCOCO2)
CCC L285
HGNC 29912
MGI 1343177
PubMed 23820297
UniProt Q13137
Wiki CALCOCO2
Calcium Binding And Coiled Coil Domain Containing Protein 2 is a subunit of nuclear domain 10 (ND10) bodies. ND10 bodies are nuclear domains appearing immunohistochemically as ten dots per nucleus. They are believed to be associated with the nuclear matrix on the basis of their resistance to nuclease digestion and salt extraction. ND10 proteins are removed from the nucleus by herpes simplex virus-1 infection and may have a role in viral life cycles.
NDP52 contains a central coiled coil with an integrated leucine zipper, multiple phosphorylation sites, and a LIM-like domain at the cysteine-rich C terminus. Northern blot analysis revealed ubiquitous expression of a 2.5-kb transcript, with highest levels in skeletal muscle and lowest levels in brain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Calcium Binding And Coiled Coil Domain Containing Protein 2 (CALCOCO2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Calcium Binding And Coiled Coil Domain Containing Protein 2 (CALCOCO2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Calcium Binding And Coiled Coil Domain Containing Protein 2 (CALCOCO2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Calcium Binding And Coiled Coil Domain Containing Protein 2 (CALCOCO2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Calcium Binding And Coiled Coil Domain Containing Protein 2 (CALCOCO2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Calcium Binding And Coiled Coil Domain Containing Protein 2 (CALCOCO2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Calcium Binding And Coiled Coil Domain Containing Protein 2 (CALCOCO2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Calcium Binding And Coiled Coil Domain Containing Protein 2 (CALCOCO2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Calcium Binding And Coiled Coil Domain Containing Protein 2 (CALCOCO2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Calcium Binding And Coiled Coil Domain Containing Protein 2 (CALCOCO2) ELISA Kit Customized Service Offer
  1. "Molecular characterization of NDP52, a novel protein of the nuclear domain 10, which is redistributed upon virus infection and interferon treatment."J. Cell Biol. 130:1-13(1995) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Cellular localization, expression, and structure of the nuclear dot protein 52."J. Cell Biol. 138:435-448(1997) [PubMed] [Europe PMC] [Abstract]
  6. "HCC-associated protein HCAP1, a variant of GEMIN4, interacts with zinc-finger proteins."J. Biochem. 133:713-718(2003) [PubMed] [Europe PMC] [Abstract]
  7. "T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion."J. Cell Sci. 120:2574-2585(2007) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]