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Complement Factor H Related Protein 3 (CFHR3)

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CFHL3; DOWN16; FHR-3; FHR3; HLF4; H factor-like protein 3

Complement Factor H Related Protein 3 (CFHR3)
CCC L329
HGNC 16980
MGI 3647418
PubMed 22626820
UniProt Q02985
Wiki CFHR3
Human complement factor H (CFH) and the 5 factor H-related proteins, CFHR1, CFHR2, CFHR3, CFHR4 , and CFHR5, are exclusively composed of highly-related short consensus repeats (SCRs), each of which contains 4 cysteine residues and additional conserved amino acids.
The deduced 331-amino acid protein has a 19-amino acid signal peptide, 4 N-linked glycosylation sites, and 5 SCRs. SCR 1 and 2 of CFHL3 are homologous to SCR 6 and 7 of CFH, whereas SCR 3, 4, and 5 of CFHR3 are somewhat less homologous to SCR 8, 19, and 20 of CFH. Northern blot analysis revealed expression of a 1.4-kb CFHR3 transcript in liver. Autoradiographic analysis determined that CFHR3 is secreted as a 37.5-kD protein.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL329Hu01 Recombinant Complement Factor H Related Protein 3 (CFHR3) Positive Control; Immunogen; SDS-PAGE; WB.
APL329Hu01 Active Complement Factor H Related Protein 3 (CFHR3) Cell culture; Activity Assays.
RPL329Hu02 Recombinant Complement Factor H Related Protein 3 (CFHR3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAL329Hu01 Polyclonal Antibody to Complement Factor H Related Protein 3 (CFHR3) WB; IHC; ICC; IP.
MAL329Hu21 Monoclonal Antibody to Complement Factor H Related Protein 3 (CFHR3) WB; IHC; ICC; IP.
Assay Kits SEL329Hu ELISA Kit for Complement Factor H Related Protein 3 (CFHR3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Complement Factor H Related Protein 3 (CFHR3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Complement Factor H Related Protein 3 (CFHR3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Complement Factor H Related Protein 3 (CFHR3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Complement Factor H Related Protein 3 (CFHR3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Complement Factor H Related Protein 3 (CFHR3) ELISA Kit Customized Service Offer
  1. "A novel short consensus repeat-containing molecule is related to human complement factor H."J. Biol. Chem. 268:2904-2908(1993) [PubMed] [Europe PMC] [Abstract]
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  7. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]