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C-Type Lectin Domain Family 5, Member A (CLEC5A)

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CLECSF5; MDL-1; C-type lectin superfamily member 5; Myeloid DAP12-associating lectin 1

C-Type Lectin Domain Family 5, Member A (CLEC5A)
CCC L351
HGNC 2054
MGI 1345151
PubMed 23152543
RGD 1584755
UniProt Q9NY25
Wiki CLEC5A
CLEC5Aencodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation.
The predicted Clecsf5 protein is a type II transmembrane protein consisting of a short, 2-amino acid intracellular region, a transmembrane domain containing a positively charged amino acid that enables it to pair with Dap12, and an extracellular domain containing characteristic structural motifs of the C-type lectin superfamily.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C-Type Lectin Domain Family 5, Member A (CLEC5A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C-Type Lectin Domain Family 5, Member A (CLEC5A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C-Type Lectin Domain Family 5, Member A (CLEC5A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C-Type Lectin Domain Family 5, Member A (CLEC5A) CLIA Kit Customized Service Offer
n/a ELISA Kit for C-Type Lectin Domain Family 5, Member A (CLEC5A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C-Type Lectin Domain Family 5, Member A (CLEC5A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C-Type Lectin Domain Family 5, Member A (CLEC5A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C-Type Lectin Domain Family 5, Member A (CLEC5A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C-Type Lectin Domain Family 5, Member A (CLEC5A) CLIA Kit Customized Service Offer
n/a ELISA Kit for C-Type Lectin Domain Family 5, Member A (CLEC5A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C-Type Lectin Domain Family 5, Member A (CLEC5A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C-Type Lectin Domain Family 5, Member A (CLEC5A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C-Type Lectin Domain Family 5, Member A (CLEC5A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C-Type Lectin Domain Family 5, Member A (CLEC5A) CLIA Kit Customized Service Offer
n/a ELISA Kit for C-Type Lectin Domain Family 5, Member A (CLEC5A) ELISA Kit Customized Service Offer
  1. "Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells."Proc. Natl. Acad. Sci. U.S.A. 96:9792-9796(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "CLEC5A is critical for dengue-virus-induced lethal disease."Nature 453:672-676(2008) [PubMed] [Europe PMC] [Abstract]
  5. "Structural flexibility of the macrophage dengue virus receptor CLEC5A: Implications for ligand binding and signaling."J. Biol. Chem. 286:24208-24218(2011) [PubMed] [Europe PMC] [Abstract]