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Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2)

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PIR121; p53 Inducible Protein

Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2)
CCC L393
HGNC 13760
MGI 1924134
PubMed 22268788
UniProt Q96F07
Wiki CYFIP2
CYFIP2 contains 1,252 amino acids and shares 88% sequence identity with CYFIP1. CYFIP1/2 are members of a highly conserved protein family and share approximately 99% sequence identity with their mouse orthologs. CYFIP1 interacts exclusively with FMRP, whereas CYFIP2 also interacts with the FMRP-related proteins FXR1P and FXR2P. The interaction of FMRP and CYFIP involves the domain of FMRP that also mediates homo- and heteromerization, suggesting a competition between interaction among the FXR proteins and interaction with CYFIP.CYFIP1/2 are distributed in an identical pattern in the cytoplasm, showing colocalization with FMRP and ribosomes. Consistent with FMRP and RAC1 localization in dendritic fine structures, CYFIP1/2 are present in synaptosomal extracts.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) ELISA Kit Customized Service Offer
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