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Enhancer Of mRNA Decapping Protein 3 (EDC3)

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LSM16; YJDC; YJEFN2; YjeF N-terminal domain-containing protein 2; YjeF domain-containing protein 1

Enhancer Of mRNA Decapping Protein 3 (EDC3)
CCC L460
HGNC 26114
MGI 2142951
PubMed 23956223
UniProt Q96F86
Wiki EDC3
EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end. EDC3 contains 508 amino acids and has an N-terminal Sm domain, followed by an FDF domain and a C-terminal YjeF-N domain. EDC3 localized with decapping proteins within cytoplasmic processing bodies in HeLa cells.
EDC3, RCK (DDX6), and HEDLS (RCD8) coimmunopurified with DCP1A and DCP2 from HEK293 cell lysates. Overexpression of DCP2, RCK, or EDC3 in HeLa cells reduced the association of endogenous DCP1A and XRN1 with cytoplasmic processing bodies. EDC3 also interacted with TTP (ZFP36) in transfected HEK293 cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
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Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Enhancer Of mRNA Decapping Protein 3 (EDC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Enhancer Of mRNA Decapping Protein 3 (EDC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Enhancer Of mRNA Decapping Protein 3 (EDC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Enhancer Of mRNA Decapping Protein 3 (EDC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Enhancer Of mRNA Decapping Protein 3 (EDC3) ELISA Kit Customized Service Offer
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