Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2)

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GalNAc-T2; Polypeptide GalNAc transferase 2; Protein-UDP acetylgalactosaminyltransferase 2; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2

Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2)
GALNT2 encodes polypeptide N-acetylgalactosaminyltransferase 2, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. The localization site of this particular enzyme is preponderantly the trans-Golgi. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation in a cell is regulated by a repertoire of GalNAc-transferases.
The GALNT2 cDNA encodes a predicted 571-amino acid protein of approximately 64 kD.GALNT1, GALNT2, and GALNT3 genes contain 11, 16, and 10 exons, respectively. Several intron/exon boundaries are conserved within the 3 genes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Polypeptide-N-Acetylgalactosaminyltransferase 2 (GALNT2) ELISA Kit Customized Service Offer
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  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
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  5. "Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3."J. Biol. Chem. 272:23503-23514(1997) [PubMed] [Europe PMC] [Abstract]
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  7. "Initiation of O-glycan synthesis in IgA1 hinge region is determined by a single enzyme, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2."J. Biol. Chem. 278:5613-5621(2003) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  10. "Dynamic association between the catalytic and lectin domains of human UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase-2."J. Biol. Chem. 281:8613-8619(2006) [PubMed] [Europe PMC] [Abstract]