C1D Nuclear Receptor Corepressor (C1D)
[Edit]SUNCOR; SUN-CoR; LRP1; Small Unique Nuclear Receptor Co-repressor; Nuclear nucleic acid-binding protein C1D
C1D is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Alternate splicing results in multiple transcript variants that encode the same protein. Multiple pseudogenes of this gene are found on chromosome 10.The full-length cDNA encodes a deduced 141-amino acid protein that shares 89% sequence identity with the mouse protein. Both proteins contain nuclear localization signals but no known DNA-binding motifs. Western blot analysis revealed expression of a 16-kD human protein, as well as a 32-kD band believed to be an SDS-resistant homodimer, in human fibroblasts.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant C1D Nuclear Receptor Corepressor (C1D) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to C1D Nuclear Receptor Corepressor (C1D) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to C1D Nuclear Receptor Corepressor (C1D) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for C1D Nuclear Receptor Corepressor (C1D) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for C1D Nuclear Receptor Corepressor (C1D) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant C1D Nuclear Receptor Corepressor (C1D) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to C1D Nuclear Receptor Corepressor (C1D) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to C1D Nuclear Receptor Corepressor (C1D) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for C1D Nuclear Receptor Corepressor (C1D) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for C1D Nuclear Receptor Corepressor (C1D) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant C1D Nuclear Receptor Corepressor (C1D) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to C1D Nuclear Receptor Corepressor (C1D) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to C1D Nuclear Receptor Corepressor (C1D) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for C1D Nuclear Receptor Corepressor (C1D) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for C1D Nuclear Receptor Corepressor (C1D) | ELISA Kit Customized Service Offer |
- "cDNA cloning, recombinant expression and characterization of polypeptides with exceptional DNA affinity."Nucleic Acids Res. 26:1160-1166(1998) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D."Genes Dev. 12:2188-2199(1998) [PubMed] [Europe PMC] [Abstract]
- "Identification of a novel Rac3-interacting protein C1D."Int. J. Mol. Med. 1:665-670(1998) [PubMed] [Europe PMC] [Abstract]
- "Induction of apoptosis by overexpression of the DNA-binding and DNA-PK-activating protein C1D."J. Cell Sci. 112:2223-2232(1999) [PubMed] [Europe PMC] [Abstract]
- "DNA damage-dependent interaction of the nuclear matrix protein C1D with Translin-associated factor X (TRAX)."J. Cell Sci. 115:207-216(2002) [PubMed] [Europe PMC] [Abstract]
- "C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing."Nucleic Acids Res. 35:2564-2572(2007) [PubMed] [Europe PMC] [Abstract]