C1D Nuclear Receptor Corepressor (C1D)

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SUNCOR; SUN-CoR; LRP1; Small Unique Nuclear Receptor Co-repressor; Nuclear nucleic acid-binding protein C1D

C1D Nuclear Receptor Corepressor (C1D)
C1D is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Alternate splicing results in multiple transcript variants that encode the same protein. Multiple pseudogenes of this gene are found on chromosome 10.The full-length cDNA encodes a deduced 141-amino acid protein that shares 89% sequence identity with the mouse protein. Both proteins contain nuclear localization signals but no known DNA-binding motifs. Western blot analysis revealed expression of a 16-kD human protein, as well as a 32-kD band believed to be an SDS-resistant homodimer, in human fibroblasts.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C1D Nuclear Receptor Corepressor (C1D) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C1D Nuclear Receptor Corepressor (C1D) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C1D Nuclear Receptor Corepressor (C1D) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C1D Nuclear Receptor Corepressor (C1D) CLIA Kit Customized Service Offer
n/a ELISA Kit for C1D Nuclear Receptor Corepressor (C1D) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C1D Nuclear Receptor Corepressor (C1D) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C1D Nuclear Receptor Corepressor (C1D) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C1D Nuclear Receptor Corepressor (C1D) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C1D Nuclear Receptor Corepressor (C1D) CLIA Kit Customized Service Offer
n/a ELISA Kit for C1D Nuclear Receptor Corepressor (C1D) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C1D Nuclear Receptor Corepressor (C1D) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C1D Nuclear Receptor Corepressor (C1D) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C1D Nuclear Receptor Corepressor (C1D) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C1D Nuclear Receptor Corepressor (C1D) CLIA Kit Customized Service Offer
n/a ELISA Kit for C1D Nuclear Receptor Corepressor (C1D) ELISA Kit Customized Service Offer
  1. "cDNA cloning, recombinant expression and characterization of polypeptides with exceptional DNA affinity."Nucleic Acids Res. 26:1160-1166(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D."Genes Dev. 12:2188-2199(1998) [PubMed] [Europe PMC] [Abstract]
  6. "Identification of a novel Rac3-interacting protein C1D."Int. J. Mol. Med. 1:665-670(1998) [PubMed] [Europe PMC] [Abstract]
  7. "Induction of apoptosis by overexpression of the DNA-binding and DNA-PK-activating protein C1D."J. Cell Sci. 112:2223-2232(1999) [PubMed] [Europe PMC] [Abstract]
  8. "DNA damage-dependent interaction of the nuclear matrix protein C1D with Translin-associated factor X (TRAX)."J. Cell Sci. 115:207-216(2002) [PubMed] [Europe PMC] [Abstract]
  9. "C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing."Nucleic Acids Res. 35:2564-2572(2007) [PubMed] [Europe PMC] [Abstract]