GLI Pathogenesis Related Protein 1 (GLIPR1)
[Edit]CRISP7; GLIPR; RTVP1; Glioma Pathogenesis-Related 1
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GLIPR1 encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer.
The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants that encode different protein isoforms have been described; however, not all variants have been fully characterized.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant GLI Pathogenesis Related Protein 1 (GLIPR1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to GLI Pathogenesis Related Protein 1 (GLIPR1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to GLI Pathogenesis Related Protein 1 (GLIPR1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for GLI Pathogenesis Related Protein 1 (GLIPR1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for GLI Pathogenesis Related Protein 1 (GLIPR1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant GLI Pathogenesis Related Protein 1 (GLIPR1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to GLI Pathogenesis Related Protein 1 (GLIPR1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to GLI Pathogenesis Related Protein 1 (GLIPR1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for GLI Pathogenesis Related Protein 1 (GLIPR1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for GLI Pathogenesis Related Protein 1 (GLIPR1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant GLI Pathogenesis Related Protein 1 (GLIPR1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to GLI Pathogenesis Related Protein 1 (GLIPR1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to GLI Pathogenesis Related Protein 1 (GLIPR1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for GLI Pathogenesis Related Protein 1 (GLIPR1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for GLI Pathogenesis Related Protein 1 (GLIPR1) | ELISA Kit Customized Service Offer |
- "The human glioma pathogenesis-related protein is structurally related to plant pathogenesis-related proteins and its gene is expressed specifically in brain tumors."Gene 159:131-135(1995) [PubMed] [Europe PMC] [Abstract]
- "RTVP-1, a novel human gene with sequence similarity to genes of diverse species, is expressed in tumor cell lines of glial but not neuronal origin."Gene 180:125-130(1996) [PubMed] [Europe PMC] [Abstract]
- "Cloning and characterization of human RTVP-1b, a novel splice variant of RTVP-1 in glioma cells."Biochem. Biophys. Res. Commun. 362:612-618(2007) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Structure comparison of human glioma pathogenesis-related protein GliPR and the plant pathogenesis-related protein P14a indicates a functional link between the human immune system and a plant defense system."Proc. Natl. Acad. Sci. U.S.A. 95:2262-2266(1998) [PubMed] [Europe PMC] [Abstract]