Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A)

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POLR2M; DNA-directed RNA polymerase II subunit M; Glutamate receptor-like protein 1A

Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A)
GRINL1A is part of a complex transcript unit that includes the gene for GRINL1A combined protein (Gcom1). Transcription of this gene occurs at a downstream promoter, with at least three different alternatively spliced variants, grouped together as Gdown for GRINL1A downstream transcripts. The Gcom1 gene uses an upstream promoter for transcription and also has multiple alternatively spliced variants.
The ionotropic glutamate receptors play roles in the development and function of the mammalian brain. Roginski et al. (2001) isolated rat GRINL1 cDNA from a size-fractionated, directional rat brain cDNA library. They obtained human GRINL1A genomic DNA sequences by amplification with primers designed from the rat sequences.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Like Protein 1A (GRINL1A) ELISA Kit Customized Service Offer
  1. "Assignment of an ionotropic glutamate receptor-like gene (GRINL1A) to human chromosome 15q22.1 by in situ hybridization."Cytogenet. Cell Genet. 93:143-144(2001) [PubMed] [Europe PMC] [Abstract]
  2. "The human GRINL1A gene defines a complex transcription unit, an unusual form of gene organization in eukaryotes."Genomics 84:265-276(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  7. "A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology."Mol. Cell 14:685-691(2004) [PubMed] [Europe PMC] [Abstract]
  8. "A Mediator-responsive form of metazoan RNA polymerase II."Proc. Natl. Acad. Sci. U.S.A. 103:9506-9511(2006) [PubMed] [Europe PMC] [Abstract]