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Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3)

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CIG49; GARG49; IFI60; IFIT4; IRG2; ISG60; RIG-G; Interferon-induced 60 kDa protein; Retinoic acid-induced gene G protein; Interferon-induced protein with tetratricopeptide repeats 4

Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3)
CCC L611
HGNC 5411
MGI 1101055
PubMed 21813773
RGD 1359681
UniProt O14879
Wiki IFIT3
Combined all-trans-retinoic acid (ATRA) and anthracycline chemotherapy results in long-term survival and potential cure in nearly 70% of patients with acute promyelocytic leukemia (APL).
IFIT4 has 1 potential glycosylation site, 1 glycosaminoglycan attachment site, and 14 potential phosphorylation sites. Northern blot analysis revealed expression of a 2.8- to 2.9-kb transcript within a few hours in IFNA-treated cells and within 12 to 24 hours in ATRA-treated cells. IFIT4 expression was low in all normal tissues tested. Indirect immunofluorescence staining showed a diffuse distribution pattern in the cytoplasm, with clustering in the perinuclear region.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Induced Protein With Tetratricopeptide Repeats 3 (IFIT3) ELISA Kit Customized Service Offer
  1. "Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs."Proc. Natl. Acad. Sci. U.S.A. 94:13985-13990(1997) [PubMed] [Europe PMC] [Abstract]
  2. "IFI60/ISG60/IFIT4, a new member of the human IFI54/IFIT2 family of interferon-stimulated genes."Genomics 54:267-277(1998) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins."Proc. Natl. Acad. Sci. U.S.A. 103:16448-16453(2006) [PubMed] [Europe PMC] [Abstract]
  5. "Interferon-induced protein IFIT4 is associated with systemic lupus erythematosus and promotes differentiation of monocytes into dendritic cell-like cells."Arthritis Res. Ther. 10:R91-R91(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Identification of alpha interferon-induced genes associated with antiviral activity in Daudi cells and characterization of IFIT3 as a novel antiviral gene."J. Virol. 84:10671-10680(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "The interferon stimulated gene 54 promotes apoptosis."J. Biol. Chem. 286:7257-7266(2011) [PubMed] [Europe PMC] [Abstract]
  12. "IFN-induced TPR protein IFIT3 potentiates antiviral signaling by bridging MAVS and TBK1."J. Immunol. 187:2559-2568(2011) [PubMed] [Europe PMC] [Abstract]
  13. "The ISG56/IFIT1 gene family."J. Interferon Cytokine Res. 31:71-78(2011) [PubMed] [Europe PMC] [Abstract]
  14. "IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA."Nat. Immunol. 12:624-630(2011) [PubMed] [Europe PMC] [Abstract]
  15. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]