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Mitochondrial Protein 18kDa (MTP18)

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MTFP1; Mitochondrial fission process protein 1

Mitochondrial Protein 18kDa (MTP18)
CCC L760
MGI 1916686
PubMed 19492057
RGD 1359705
UniProt Q9UDX5
Wiki MTP18
MTP18 is a mitochondrial protein and downstream target of the phosphatidylinositol 3-kinase signaling pathway that plays a role in cell viability and mitochondrial dynamics. The deduced 166-amino acid protein was detected as a 18-kD species by immunoblot analysis, consistent with the predicted molecular mass.
MTP18 colocalized with mitochondria by subcellular fractionation and immunoblot analysis, and by confocal microscopy of HeLa cells transfected with MTP18.FACS analysis showed that reduced MTP18 levels led to a reduction in cell proliferation with an increase in the sub-G1 fraction, suggesting an increase in DNA fragmentation and induction of apoptosis, assayed by cytochrome c release.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitochondrial Protein 18kDa (MTP18) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitochondrial Protein 18kDa (MTP18) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitochondrial Protein 18kDa (MTP18) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitochondrial Protein 18kDa (MTP18) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitochondrial Protein 18kDa (MTP18) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitochondrial Protein 18kDa (MTP18) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitochondrial Protein 18kDa (MTP18) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitochondrial Protein 18kDa (MTP18) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitochondrial Protein 18kDa (MTP18) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitochondrial Protein 18kDa (MTP18) ELISA Kit Customized Service Offer
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  6. "The mitochondrial protein MTP18 contributes to mitochondrial fission in mammalian cells."J. Cell Sci. 118:3049-3059(2005) [PubMed] [Europe PMC] [Abstract]
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