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V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1)

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AMYB; A-myb; MYBA; Myb-related protein A

V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1)
CCC L766
HGNC 7547
MGI 99925
PubMed 21750041
RGD 1306940
UniProt P10243
Nomura et al. (1988) isolated and characterized cDNA clones for 2 human MYB-related genes, and BMYB. Using probes in Southern blot analysis of rodent-human hybrid DNAs, Barletta et al. (1991) localized the MYBL1 locus to 8cen-q22 and refined the localization to 8q22-q23 by in situ hybridization. MYBL1 mRNA is expressed mainly in testis and peripheral blood leukocytes. AMYB could activate transcription from the promoter-containing MYB-binding sites in all cells examined. In addition to the 2 domains (a DNA-binding domain and a transcriptional activation domain), 2 negative regulatory domains were identified in the MYBL1 gene. These results indicated that the gene functions as a transcriptional activator and that the regulatory mechanism of gene activity is similar to that of the MYB gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Polyclonal Antibody Customized Service Offer
Assay Kits SEL766Ra ELISA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Isolation of human cDNA clones of myb-related genes, A-myb and B-myb."Nucleic Acids Res. 16:11075-11089(1988) [PubMed] [Europe PMC] [Abstract]
  4. "The human A-myb protein is a strong activator of transcription."Oncogene 9:2469-2479(1994) [PubMed] [Europe PMC] [Abstract]
  5. "DNA binding and transactivation activity of A-myb, a C-myb-related gene."Cancer Res. 54:6512-6516(1994) [PubMed] [Europe PMC] [Abstract]
  6. "Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence."Mol. Cell 26:539-551(2007) [PubMed] [Europe PMC] [Abstract]
  7. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]