Zinc Finger Protein 33B (ZNF33B)

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KOX2; KOX31; ZNF11B

Zinc Finger Protein 33B (ZNF33B)
By a combination of in situ chromosomal hybridization and somatic cell hybrid analysis, Rousseau-Merck et al. (1992) concluded that there are sequences hybridizing to the KOX2 probe at 2 loci, which they called ZNF11A (ZNF33A) and ZNF11B (ZNF33B), that map proximal and distal to a 10q11.2 breakpoint, respectively. They suggested that the 2 ZNF11 loci represent related sequences. Tunnacliffe et al. (1993) identified 2 related zinc finger gene clusters mapping to the pericentromeric region of chromosome 10. Cluster A contains ZNF11A (ZNF33A) and ZNF37A and maps to chromosome 10p11.2. Cluster B contains ZNF11B (ZNF33B) and ZNF37B and maps to chromosome 10q11.2. Southern blot analysis indicated that the 2 clusters evolved by duplication of an ancestral gene cluster before the divergence of the human and great ape lineages.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 33B (ZNF33B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 33B (ZNF33B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 33B (ZNF33B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 33B (ZNF33B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 33B (ZNF33B) ELISA Kit Customized Service Offer
  1. "Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10p."Genome Res. 13:159-172(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution."Nucleic Acids Res. 21:1409-1417(1993) [PubMed] [Europe PMC] [Abstract]
  5. "Multiple genes encoding zinc finger domains are expressed in human T cells."New Biol. 2:363-374(1990) [PubMed] [Europe PMC] [Abstract]