Xin Actin Binding Repeat Containing Protein 2 (XIRP2)

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CMYA3; Xeplin; Beta-xin; Cardiomyopathy Associated 3

Xin Actin Binding Repeat Containing Protein 2 (XIRP2)
XIRP2contains 28 Xin repeats within a region spanning about 1,000 amino acids. EST database analysis indicated that XIRP2 is expressed in heart, tongue, and skeletal muscle.
The deduced protein contains 3,283 amino acids. Northern blot analysis detected myomaxin expression in heart and skeletal muscle only. Western blot analysis confirmed myomaxin expression in striated muscle. Immunohistochemical analysis showed robust myomaxin expression in a striated pattern in mouse heart, and myomaxin colocalized with alpha-actinin-2 (ACTN2) at Z discs.Myomaxin expression was upregulated upon differentiation in cultured mouse myoblasts and by hypertrophic stimuli in neonatal rat cardiomyocytes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Xin Actin Binding Repeat Containing Protein 2 (XIRP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Xin Actin Binding Repeat Containing Protein 2 (XIRP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Xin Actin Binding Repeat Containing Protein 2 (XIRP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Xin Actin Binding Repeat Containing Protein 2 (XIRP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Xin Actin Binding Repeat Containing Protein 2 (XIRP2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Xin Actin Binding Repeat Containing Protein 2 (XIRP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Xin Actin Binding Repeat Containing Protein 2 (XIRP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Xin Actin Binding Repeat Containing Protein 2 (XIRP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Xin Actin Binding Repeat Containing Protein 2 (XIRP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Xin Actin Binding Repeat Containing Protein 2 (XIRP2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Xin Actin Binding Repeat Containing Protein 2 (XIRP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Xin Actin Binding Repeat Containing Protein 2 (XIRP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Xin Actin Binding Repeat Containing Protein 2 (XIRP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Xin Actin Binding Repeat Containing Protein 2 (XIRP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Xin Actin Binding Repeat Containing Protein 2 (XIRP2) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Xin repeats define a novel actin-binding motif."J. Cell Sci. 117:5257-5268(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]