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Wingless Type MMTV Integration Site Family, Member 2 (WNT2)

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IRP; INT1L1; Secreted Growth Factor; Int-1-related protein

Wingless Type MMTV Integration Site Family, Member 2 (WNT2)
CCC L820
HGNC 12780
MGI 98954
PubMed 19686689
RGD 621346
UniProt P09544
WNT2 is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins which are involved in the Wnt signaling pathway. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene.
The INT1-related protein is an additional member of the INT1 growth factor gene family. Because of its homology to protooncogene INT1, IRP is also symbolized INT1L1. IRP is expressed in a variety of fetal and adult human tissues that do not overlap with the pattern of expression of INT1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL820Hu01 Recombinant Wingless Type MMTV Integration Site Family, Member 2 (WNT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAL820Hu01 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 2 (WNT2) WB; IHC; ICC; IP.
MAL820Hu21 Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 2 (WNT2) WB; IHC; ICC; IP.
Assay Kits SEL820Hu ELISA Kit for Wingless Type MMTV Integration Site Family, Member 2 (WNT2) Enzyme-linked immunosorbent assay for Antigen Detection.
SCL820Hu CLIA Kit for Wingless Type MMTV Integration Site Family, Member 2 (WNT2) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL820Mu01 Recombinant Wingless Type MMTV Integration Site Family, Member 2 (WNT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 2 (WNT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 2 (WNT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Wingless Type MMTV Integration Site Family, Member 2 (WNT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Wingless Type MMTV Integration Site Family, Member 2 (WNT2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Wingless Type MMTV Integration Site Family, Member 2 (WNT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 2 (WNT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 2 (WNT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Wingless Type MMTV Integration Site Family, Member 2 (WNT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Wingless Type MMTV Integration Site Family, Member 2 (WNT2) ELISA Kit Customized Service Offer
  1. "Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless."EMBO J. 7:1743-1748(1988) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Evidence supporting WNT2 as an autism susceptibility gene."Am. J. Med. Genet. 105:406-413(2001) [PubMed] [Europe PMC] [Abstract]
  7. "No association between the WNT2 gene and autistic disorder."Am. J. Med. Genet. 114:106-109(2002) [PubMed] [Europe PMC] [Abstract]